VWF and stroke disorder: vWF, a soluble protein involved in hemostasis23, was associated with both venous thrombosis (e.g., deep vein thrombosis [OR = 1.24 {1.18–1.29}]) and arterial thrombosis (including stroke [OR = 1.11 {1.06–1.16}] and “Acute vascular insufficiency of intestine” [OR = 1.21 {1.09–1.34}]) (Fig. 4d).