SNHG5 and hepatocellular carcinoma: Firstly, growth curves measured by MTT assay showed that downregulation of SNHG5 significantly decreased HCC cell growth (Fig. 2b), and colony formation assay verify this results by demonstrated that SNHG5 knockdown caused a decrease in the clonogenic survival of HepG2 and MHCC-97L cells compared with negative control (NC) (Fig. 2c).