ATM and ataxia-telangiectasia-like disorder: Hypomorphic MRE11 mutations are responsible for the inherited Ataxia-Telangiectasia-like disorder (ATLD), which shares cellular and clinical phenotypes (including immunodeficiency, sterility, and radiosensitivity) with Ataxia Telangiectasia (A-T) and Nijmegen breakage syndrome (NBS), caused by mutations in the ATM and NBS1 genes, respectively5,6.