TNNI3 and chronic obstructive pulmonary disease: As such, high-sensitivity cardiac troponin I represents a plausible surrogate indicator of the CV consequences of novel medical therapies and interventions.PerspectivesCOMPETENCY IN MEDICAL KNOWLEDGE: In patients with COPD, plasma concentrations of cardiac troponin I are associated with future fatal and nonfatal CV events but not with exacerbations of COPD.