One explanation may lie with the different pattern recognition receptors engaged in lipid droplet biogenesis in the two infections: lipid droplet formation in M. leprae-infected cells requires both Toll-like receptor 2 (TLR2) and TLR6 [75], while M. tuberculosis-induced lipid droplets require TLR2, but not TLR-6 [76]. The gene discussed is TLR2; the disease is infection.