We analysed the microarray data on Gene Expression Omnibus (GSE29801 and GSE10965).44 In these group microarray data, we analysed expression of ATP1B1 and ATP1A1 in RPE of young and old mice and 175 samples from the macular or extramacular region of human donor eye RPE‐choroids and 118 samples from the macular or extramacular region of human donor retina with no reported ocular disease, possible preclinical AMD or AMD. The gene discussed is ATP1A1; the disease is age-related macular degeneration.