C1QBP and cancer: C1QBP was reported to be proapoptotic and is significantly upregulated during cisplatin‐induced apoptosis in HeLa cells.20, 27 Interactions between mitochondrial C1QBP and tumor suppressor p14/ARF28 or the prodeath Bcl‐2 family protein HRK29 are necessary for inducing mitochondria‐dependent cell death in cancer cells.