CD274 and non-small cell lung carcinoma: Two antibodies (nivolumab and pembrolizumab) to PD-1 and two antibodies (atezolizumab and durvalumab) to PD-L1 have been approved by the US Food and Drug Administration (FDA) and/or European Medicines Agency (EMA) for treatment of NSCLC (Table 1) [13–16].