CD274 and non-small cell lung carcinoma: However, a randomized phase II study in investigation of the efficacy and safety of atezolizumab comparing with docetaxel in previous platinum-treated NSCLC patients (who were PD-L1-positive as determined by SP142 antibody IHC assay) showed that atezolizumab resulted in an enhanced PFS (9.7 versus 3.9 months) and OS compared to docetaxel (12.2 versus 9.4 months) for patients with high levels of PD-L1 expression (NCT01903993) [54].