More studies brought up that the mutation of RTEL1 had been linked to dyskeratosis congenital [43], Hoyeraal-Hreidarsson syndrome [44], pulmonary fibrosis [45], myelodysplastic syndrome [46], and lung cancer [47] and even rheumatoid arthritis-associated interstitial lung disease [48]. The gene discussed is RTEL1; the disease is Hoyeraal-Hreidarsson syndrome.