NR4A1 and rheumatoid arthritis: We found that signal pathways “cytokine-cytokine receptor interaction,” “NF-kappa B signaling pathway,” “FoxO signaling pathway,” and “chemokine signaling pathway” were shared by RA, pSS, and SLE, and the top 10 GO terms in Figure 5(c) were related to “cytokine-cytokine interaction” and “NF-kappa B signaling pathway.” Interestingly, “glucocorticoid receptor binding” and “hormone receptor binding” were also enriched from hypomethylated cytokines in SLE, but they were enriched from hypermethylated genes in RA.