We found that signal pathways “cytokine-cytokine receptor interaction,” “NF-kappa B signaling pathway,” “FoxO signaling pathway,” and “chemokine signaling pathway” were shared by RA, pSS, and SLE, and the top 10 GO terms in Figure 5(c) were related to “cytokine-cytokine interaction” and “NF-kappa B signaling pathway.” Interestingly, “glucocorticoid receptor binding” and “hormone receptor binding” were also enriched from hypomethylated cytokines in SLE, but they were enriched from hypermethylated genes in RA. The gene discussed is NR3C1; the disease is rheumatoid arthritis.