HMOX1 and obstructive sleep apnea syndrome: After adjusting for the influence of age, education, sex, and smoking index, the expression of Nrf2-ARE signaling pathway components in patients with OSAHS, including total Nrf2 protein, nuclear Nrf2 protein in PBMCs, and plasma Trx levels, were all correlated with TSat90 and AHI, and HO-1 protein levels were correlated with LSaO2, MSaO2, ODI, and TSat90.