Several large multi-omics studies have shown that ICC and HCC share recurrently mutated genes including TP53, BAP1, ARID1A, ARID2 (Chaisaingmongkol et al., 2017; Farshidfar et al., 2017; Wang et al., 2018). The gene discussed is TP53; the disease is intrahepatic cholangiocarcinoma.