FAS and familial pancreatic carcinoma: Recently, Kaur et al. have shown that treatment with rfhSP-D for 48 h differentially induced apoptosis in pancreatic cancer cell lines, such as Panc-1, MiaPaCa-2, and Capan-2 via Fas-mediated pathway, involving cleavage of caspase 8 and 3 (29).