Furthermore, miR-122 inhibition was linked to the development of hemochromatosis by up-regulating the expression of human hemochromatosis protein (Hfe), hemojuvelin (Hjv), bone morphogenetic protein receptor type 1A (Bmpr1a) and the hepcidin antimicrobial peptide (Hamp) (Castoldi et al., 2011). This evidence concerns the gene HAMP and hemochromatosis type 1.