To further study the contribution of NaV1.6 channels to the invasiveness of cervical cancer25, we used commercially available CeCa cell lines; however, exhaustive patch-clamp whole-cell recordings in four different CeCa cell lines provided no evidence of voltage-gated sodium currents, except in C33A cells (characterized for being negative to any HPV type), which displays very small endogenous sodium currents (Fig. 5B). The gene discussed is SCN8A; the disease is cervicitis.