CXCL1 and breast cancer: Using the Oncomine database, the Sorlie breast study suggested that high CXCL1 expression was significantly correlated with overall survival (OS, P = 0.0186) and recurrence-free survival (RFS, P = 0.0442)19, indicating that high CXCL1 expression might predict a poor prognosis of breast cancer (Fig. 7c).