TLR3 and cancer: Conversely, 5 out of 9 (60%) SCLC and 18 out of 30 (60%) SC expressed TLR3 but at a much lower level (median scores of 10 for both, P < 0.0001), indicating that either TLR3 is lost in these types of cancers or that they arise from a different cell of origin (Table 1, and Fig. 1c, d).