PRKAA1 and steatosis: However, ATX exerts a better effect on several functional targets of detailed anti-steatosis, such as decrease in ROS generation, cell apoptosis, ER stress and lipogenesis marker genes, lipid metabolism-related genes, inflammatory cytokine and NF-κB genes, and NF-κB subunit p65-immunostained expression; further, it increases the free radical scavenging effect, antioxidant genes, AMPK phosphorylation, and FA β-oxidation.