IL6ST and inherited lipid metabolism disorder: According to the law of Mendelian randomization [56, 57], the genetic loci IL6ST is associated with IgG N-glycosylation and has an effect on dyslipidaemia, indicating that the change of galactosylation and inflammation is the intermediate phenotype between IL6ST and dyslipidaemia and is thus the causal factor of dyslipidaemia.