Pilichiewicz et al. demonstrated a significant correlation between the FD symptoms and plasma cholecystokinin, suggesting the possible involvement of gut hormones.45,57 Hence, we speculate that MEC may be helpful in alleviating at least some of the FD symptoms (e.g., delayed gastric emptying) by enhancing the action of digestive enzymes, especially in conditions such as postprandial distress syndrome. Here, CCK is linked to Fabry disease.