Statin medications target 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase (HMG Co‐A reductase), which is a key enzyme in cholesterol synthesis and also plays a key role in the biosynthesis of CoQ10.40, 41 Our results demonstrate that patients with acute influenza infection have lower circulating CoQ10 levels at the time that they were enrolled in the trial. This evidence concerns the gene HMGCR and influenza.