HNF1A and acute liver failure: Since miR-122 increases around the time of the onset of acute liver failure and liver damage or drug-induced hepatitis can promote elevated liver enzyme and miR-122 levels [35, 36], to identify a real association between HNF1A and miR-122, all subjects with elevated liver enzymes and patients receiving agents that affect the miR-122 level, such as statins, and patients consuming alcohol, were excluded in this study.