Besides capsaicin, other TRP channel agonists have been described as migraine triggers (Kunkler et al., 2011), thereby placing TRPV1, TRPA1, and TRPM8 in the therapeutic spotlight for the development of migraine treatments (Nassini et al., 2010; Oxford and Hurley, 2013; Dussor et al., 2014). Here, TRPV1 is linked to migraine disorder.