The bacterium can also induce the expression of IL-17 from peripheral blood mononuclear cells and promote Th17 and Th1 response pathways (Agak et al., 2014); activation of the Th17 axis and Th17 cytokines (IL-17, IL-1β, IL-6, and TGF-β) appears to play a pivotal role in acne (Sardana and Verma, 2017). Here, IL1B is linked to acne.