Specific diagnostic tools routinely employed included the following: ESR or CRP (Rheum 75.8%, Neph 50%, p=0.0019), ANCA titer (63.0%, p=0.1473), hematuria and/or proteinuria (73.9%, p=0.1038), and 9.4% (p=0.4970) use the Birmingham Vasculitis Activity Score. The gene discussed is CRP; the disease is vasculitis.