PIK3CB and cancer: In addition, we observed 15 and 14 cancer driver genes, respectively, from a 299 pan-cancer driver gene set provided by a recent study of TCGA’s Pan-Cancer34 in UAGs and DAGs, such as ERBB2 (level 1 driver gene in OncoKB33), TNFAIP3 in UAGs, and MAPK1, PIK3CB in DAGs (driver genes mapped in UAGs and DAGs are listed in Supplementary Table 8).