MMP8 and Peri-Implantitis: Increased levels of especially active MMP-8 (aMMP-8), but not latent, inactive proform, have been found in periodontitis- and peri-implantitis-affected oral fluids (saliva, mouth rinse, gingival crevicular fluid (GCF), and peri-implant sulcular fluid (PISF)) [8–10].