IFNG and malaria: IFN-γ has been demonstrated to effectively induce parasite killing by monocytes and neutrophils [29]; therefore, this observation implies that low production of IFN-γ during clinical malaria episodes may negatively affect the infant's ability to clear the malaria parasites, a finding that may be corroborated by an earlier study [33] that demonstrated the presence of hyperparasitaemia in exposed infants during clinical malaria episodes.