In the multinomial logical regression analysis of independent predictors of CRC staging, it has been shown that from II to IV stages of this cancer all tracked biomarkers, other than IL-6, have a significant predictive value (p <0.05) in assessing colorectal cancer stage, but from stages III to IV none of the monitored biomarkers had not a significant predictive value in the assess of colorectal cancer stage (Table 2). The gene discussed is IL6; the disease is colorectal cancer.