By analyzing the correlation of the investigated parameters in all patients with CRC (stages II, III, and IV, a total of 75 patients), significant positive correlation between IL-6 and MMP-9 serum levels was confirmed (rho=0.478; p <0.001) (Figure 1), as well as between IL-6 and CRP serum levels (rho=0.720; p <0.001) (Figure 2) and between MMP-9 and CRP serum levels (rho = 0.379; p = 0.001) (Figure 3). The gene discussed is IL6; the disease is colorectal carcinoma.