Different biomarkers such as erythrocyte sedimentation rate (ESR), CRP, IL-2, IL-3, IL-4, IL-6, IL-8, TNF-α, IFN-γ, MMPs, TIMP1, vascular cell adhesion molecules, RANTES (Regulated on Activation, Normal T Cell Expressed and Secreted), and pentraxin 3 were associated with TA disease activity (114–122); however, none of them is validated for predicting outcome and only ESR and CRP are available in routine clinical practice. The gene discussed is CRP; the disease is Takayasu arteritis.