IL1B and Behcet disease: On the other hand, several genetic associations have also been identified in BD, including mainly the genes encoding for HLA-B51, IL-6, IL-10, IL-1β, IL-12R/IL-23R, intracellular adhesion molecule, nitric oxide, chemokine receptor type 5, toll-like receptors, and fucosyltransferase 2 (130).