These studies have shown genome-wide significant associations with HLA class I (especially HLA-B51), IL10, IL23R-IL12RB2, ERAP1, STAT4, GIMAP, CCR1, KLRC4, FUT2, IL12A, NAALADL2, YIPF7, KIAA1529, CPVL, LOC100129342, UBASH3B, and UBAC2 regions in BD (27–35). This evidence concerns the gene ERAP1 and Behcet disease.