L. lactis (pXIES:CYT:15lox-1)-fermented milk was effective in the prevention of intestinal damage associated with inflammatory bowel disease (IBD) in a trinitrobenzenesulfonic acid-induced IBD mouse model (Saraiva et al., 2015) and, in addition, a decrease in IFN-γ and IL-4 was also observed. The gene discussed is IL4; the disease is inflammatory bowel disease.