Both active and inactive sarcoidosis patients had statistical significantly higher neopterin, ADA, YKL-40, sIL-2R and ACE levels (for all p < 0.001) than control subjects; and also, the hs-CRP levels of both patient group were greater than controls (for active sarcoidosis patients p < 0.001; for inactive sarcoidosis patients p < 0.05). The gene discussed is ACE; the disease is sarcoidosis.