CMA1 and chronic obstructive pulmonary disease: Chymase inhibitors like BAY 1142524, RO5066852, TY-51469, JNJ-10311795, and many others have been tested in PF, atherosclerosis, and inflammation (Figure 1 and Figure 2) [83,124,125,126] but studies relating to their effect on COPD have been very limited.