IDH1 and neoplasm: As presented in Table 2, low IDH1 expression in tumor was an unfavorable independent predictor for OS and RFS of ccRCC patients (OS, HR, 0.500, 95% CI, 0.253–0.987, p = 0.046; RFS, HR, 0.463, 95% CI, 0.233–0.922, p = 0.028).