In recent years, there were several nomograms predicting treatment failure or survival in patients with cervical cancer treated with CCRT.17–21 In these studies, the risk factors of OS, DFS, and distant failure included adenocarcinoma,17,19,21 larger tumor size,17–20 parametrium involvement,18 advanced stage,17,20 MLNs,17,20,21 high SCC antigen level,18,21 etc. Nomograms based on these factors could accurately predict prognosis and treatment failure. This evidence concerns the gene SERPINB3 and neoplasm.