DICER1 and Infertility: In females, Dicer1 loss causes abnormal spindle formation and chromosomal misalignment (Liu et al.,2010), failures in meiotic maturation and polar body formation (Murchison et al.,2007; Liu et al.,2010) and functional defects including impaired granulosa cell (GC) proliferation and steroidogenesis, recruitment of immature follicles, follicular atresia, a smaller pool size of pre‐ovulatory follicles, and ovulatory dysfunction followed by infertility (Murchison et al.,2007; Hong et al.,2008; Lei et al.,2010).