Patient’s cardiovascular risk analysis panel revealed that she had increased venous thrombosis risk with homozygous MTHFR (A 1298C) polymorphism, HPA 1 (b/b), factor V Leiden (G1691A) heterozygous and ACE I/D genotype (Del/Del); other panel polymorphisms were normal (MTHFR C677T polymorphism was C677C, factor XIII V34L polymorphism was V34LL, PAI- Serpine1 mutation 4G/5G test was 5G/5G, Prothrombin G20210A was 20210GG, Beta Fibrinogen 455A > G polymorphism was 455G > G, APO B R3500Q polymorphism was 3500RR). Here, SERPINE1 is linked to Venous thrombosis.