Eun YG et al. [44] reported that, after uvulopalatopharyngoplasty and radiofrequency tongue base reduction, OSA patients had decreased leptin and increased adiponectin expression, which suggests adipokines may respond to a single surgery within a range of OSA severities (mild, moderate, and severe) better than in patients with severe OSA. Here, ADIPOQ is linked to obstructive sleep apnea syndrome.