The goal was also to establish the correlation of the Sdc1 expression with clinical and tumor parameters and the expression of the estrogen/progesterone receptors (ERs/PRs) and HER2/neu oncoprotein in both types of primary tumors and to determine the possibility of defining and isolating the group of tumors with more aggressive biological behavior prone to metastasis. The gene discussed is PGR; the disease is neoplasm.