CDH1 and neoplasm: To further investigate the correlations between Tbx3 and E-cadherin, we observed that the ratio of the quantity of Tbx3 mRNA between tumor and non-tumor tissues was negatively associated with that of E-cadherin (R = −0.303, p < 0.05) (Fig. 4b), which demonstrates an obvious reverse-correlation between the expression levels of Tbx3 and E-cadherin.