CD8A and cancer: While such observations in CX3CR1 expression by T cells were consistent among obese and non-obese EAC patients, there were significantly higher frequencies of CX3CR1+ CD8+ T cells in the circulation of non-cancer controls, compared to EAC patients (non-cancer versus EAC: 70.33 versus 48.87%, p < 0.05, Figure 2E; Table 2).