We found that, in HD fibroblasts, inhibition of NFκB by TPCA-1 preferentially inhibited the response to IL-17A (Figure 3A, left panel), while inhibition of PI3K/Akt by Ly294002 preferentially inhibited the response to TGF-β (Figure 3A, right panel). This evidence concerns the gene TGFB1 and Huntington disease.