ECP (eosinophil-specific antibody) immunohistochemistry indicated that, in both the neutrophils-dominant and conventional asthma groups, eosinophil infiltration was present and was greater than that observed in the saline group, and the neutrophils-dominant asthma group increased more, but not significantly from the conventional asthma animals. The gene discussed is RNASE3; the disease is asthma.