One most common dystroglycanopathy caused by mutations in the fukutin-related protein (FKRP) gene manifests a wide range of disease severity from mild limb girdle muscular dystrophy (LGMD) 2I to severe congenital muscular dystrophy (CMD), Walker–Warburg syndrome, and muscle–eye–brain disease8–10. This evidence concerns the gene FKRP and congenital muscular dystrophy.