SIGLEC1 and mal de Meleda: Moreover, MDM infections with Gag p6 (Δp6), NC (ΔNCp6), MA (ΔMA) truncation mutants, or Gag start codon mutant (ATG*) (Fig. 2d, e, h) that results in initiation of Gag translation from an in-frame internal ATG present at the N-terminus of CA (leading to expression of aberrant Gag; Supplementary Fig. 2b) failed to abrogate CD169 or IP-10 induction (Fig. 2f, g, i, j).