Biomarkers such as Marker Of Proliferation Ki-67 (Ki-67), p16IN4a, a tumor suppressor protein in humans encoded by CDKN2A gene and BDProExC, a recently developed immunocytochemical assay that targets the expression of topoisomerase II-alpha and minichromosome maintenance protein-27 have been suggested as biomarkers for improving the clinical performance of cervical cancer screening3. The gene discussed is MKI67; the disease is cervical cancer.