CXCR4 and neoplasm: As shown in Figure 2C, the tumor burden after OVV-CXCR4-A-Fc treatment was significantly reduced compared with control (p < 0.001) and OVV-Fc-treated mice (p = 0.026), resulting in dormancy that extended for a period of over 1 week in the majority of treated mice (Figure 2D).