GSN and acute myeloid leukemia: Considering that (i) a number of glycosphingolipids (GSLs) is involved in the differentiation of AML cells [174] and (ii) GSN is one of the universal carriers/scavengers of S1P and ceramide (CER) binding protein [27,175], it was suggested that the average gelsolin concentration in the plasma of ALM patients differs from the levels detected in healthy subjects.