COL4A1 and breast cancer: In addition, Miyake et al. reported an increased abundance of COL4A1, COL13A1 and the combination of both collagens (COL4A1 + COL13A1) in BC urinary biopsies compared to healthy controls (sensitivity 68.2%, 54.6% and 72.1%; specificity 68.9%, 77.1% and 65.6%, respectively) [203].