APOA1 and breast cancer: Additionally, multiple studies have validated the importance of different apoliprotein types, reporting an increased abundance of APOA-1 in urine of BC patients (89–94.6% sensitivity and 85–92% specificity) compared to control patients, as well as an upregulation of APOA-2 (AUC = 0.631–0.864) in BC patients compared to hernia patients [183,198,201].