INS and type 2 diabetes mellitus: However, a recent meta-analysis by Zhu et al. of nine studies performed in T2DM was only able to confirm a beneficial effect of resveratrol for reducing HOMA-IR [15], while other clinical studies examining the influence of resveratrol on diabetes biomarkers (i.e., insulin sensitivity and glucose tolerance) have been inconclusive, making the interpretation of results difficult [16,17].