UBE2E3 and congenital myasthenic syndrome: Moreover, E3 ubiquitin-protein ligase and peptidoglycan-binding LysM domain-containing protein both play important roles in the plant defence response [23,25,26,27,28,29,30] and nicotianamine synthase is involved in the cellular response to ethylene stimulus [31]: these genes were distinguished significantly upregulated in ogu CMS abortive buds, suggesting their likely involvement in ogu CMS bud abortion.